Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 2C' and Ligand = 'BDBM50527867'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50527867 (CHEMBL4522558) Show SMILES Cl.CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccn1)C[C@H]1C[C@@H]1c1cccc(Cl)c1Cl |r| Show InChI InChI=1S/C29H33Cl2N3O.ClH/c1-2-17-34(20-23-19-25(23)24-8-7-9-26(30)28(24)31)18-6-5-16-33-29(35)22-13-11-21(12-14-22)27-10-3-4-15-32-27;/h3-4,7-15,23,25H,2,5-6,16-20H2,1H3,(H,33,35);1H/t23-,25+;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	45	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
ShanghaiTech University Curated by ChEMBL					Assay Description Displacement of [3H]-Mesulergine from recombinant human 5HT2C receptor expressed in HEKT cell membranes measured after 90 mins by microbeta scintilla...				J Med Chem 63: 4579-4602 (2020) Article DOI: 10.1021/acs.jmedchem.9b01835 BindingDB Entry DOI: 10.7270/Q2F1935W
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 2C (Homo sapiens (Human))	BDBM50527867 (CHEMBL4522558) Show SMILES Cl.CCCN(CCCCNC(=O)c1ccc(cc1)-c1ccccn1)C[C@H]1C[C@@H]1c1cccc(Cl)c1Cl |r| Show InChI InChI=1S/C29H33Cl2N3O.ClH/c1-2-17-34(20-23-19-25(23)24-8-7-9-26(30)28(24)31)18-6-5-16-33-29(35)22-13-11-21(12-14-22)27-10-3-4-15-32-27;/h3-4,7-15,23,25H,2,5-6,16-20H2,1H3,(H,33,35);1H/t23-,25+;/m1./s1	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	738	n/a	n/a	n/a	n/a
ShanghaiTech University Curated by ChEMBL					Assay Description Agonist activity at human 5HT2C receptor stably expressed in HEK293 cells co-expressing Gq assessed as induction of calcium mobilization measured at ...				J Med Chem 63: 4579-4602 (2020) Article DOI: 10.1021/acs.jmedchem.9b01835 BindingDB Entry DOI: 10.7270/Q2F1935W
					More data for this Ligand-Target Pair