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Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 3A/3B' and Ligand = 'BDBM50076419'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 3A/3B


(Rattus norvegicus-RAT)		BDBM50076419
PNG
(4-Adamantan-1-yl-2-(4-methyl-piperazin-1-yl)-quino...)
Show SMILES CN1CCN(CC1)c1cc(c2ccccc2n1)C12C[C@H]3C[C@H](C[C@H](C3)C1)C2 |THB:22:21:18:25.23.24,22:23:18:26.21.20|
Show InChI InChI=1S/C24H31N3/c1-26-6-8-27(9-7-26)23-13-21(20-4-2-3-5-22(20)25-23)24-14-17-10-18(15-24)12-19(11-17)16-24/h2-5,13,17-19H,6-12,14-16H2,1H3/t17-,18+,19-,24?
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem
Article
PubMed
 80n/an/an/an/an/an/an/an/a



Universit£ di Siena

Curated by ChEMBL


Assay Description
Inhibition of [3H]granisetron binding to 5-hydroxytryptamine 3 receptor (5-HT 3 receptor) of rat cortex and hippocampus tissue

J Med Chem 42: 1556-75 (1999)


Article DOI: 10.1021/jm981112s
BindingDB Entry DOI: 10.7270/Q2D50NPW
More data for this
Ligand-Target Pair