Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50079306'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 4 (GUINEA PIG)	BDBM50079306 (3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...) Show SMILES CC(C)n1c2ccccc2n(C(=O)NCCN2CCN(C)CC2)c1=O Show InChI InChI=1S/C18H27N5O2/c1-14(2)22-15-6-4-5-7-16(15)23(18(22)25)17(24)19-8-9-21-12-10-20(3)11-13-21/h4-7,14H,8-13H2,1-3H3,(H,19,24)	PDB UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	91	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
FAES, S.A. Curated by ChEMBL					Assay Description Binding affinity against 5-hydroxytryptamine 4 receptor in guinea pig striatum using [3H]GR-113808 as radioligand				J Med Chem 42: 2870-80 (1999) Article DOI: 10.1021/jm981098j BindingDB Entry DOI: 10.7270/Q24X58GN
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 4 (Homo sapiens (Human))	BDBM50079306 (3-Isopropyl-2-oxo-2,3-dihydro-benzoimidazole-1-car...) Show SMILES CC(C)n1c2ccccc2n(C(=O)NCCN2CCN(C)CC2)c1=O Show InChI InChI=1S/C18H27N5O2/c1-14(2)22-15-6-4-5-7-16(15)23(18(22)25)17(24)19-8-9-21-12-10-20(3)11-13-21/h4-7,14H,8-13H2,1-3H3,(H,19,24)	PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	91.9	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
INSERM Curated by ChEMBL					Assay Description Tested for 5-hydroxytryptamine 4 receptor antagonist activity				J Med Chem 46: 319-44 (2003) BindingDB Entry DOI: 10.7270/Q2T72J6J
					More data for this Ligand-Target Pair