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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50499440'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 4


(Homo sapiens (Human))		BDBM50499440
PNG
(CHEMBL3741062)
Show SMILES CC(C)c1nc(C(=O)NCC2(C)CCN(CC3CCOCC3)CC2)c2ccccn12
Show InChI InChI=1S/C24H36N4O2/c1-18(2)22-26-21(20-6-4-5-11-28(20)22)23(29)25-17-24(3)9-12-27(13-10-24)16-19-7-14-30-15-8-19/h4-6,11,18-19H,7-10,12-17H2,1-3H3,(H,25,29)
PDB

UniProtKB/SwissProt

antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 53n/an/an/an/a



Suven Life Sciences Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay

Eur J Med Chem 103: 289-301 (2015)


Article DOI: 10.1016/j.ejmech.2015.08.051
BindingDB Entry DOI: 10.7270/Q20C4ZST
More data for this
Ligand-Target Pair