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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 4' and Ligand = 'BDBM50499442'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
5-hydroxytryptamine receptor 4


(Homo sapiens (Human))		BDBM50499442
PNG
(CHEMBL3740278)
Show SMILES CC(C)c1nc(C(=O)NCC2(F)CCN(CC3CCOCC3)CC2)c2ccccn12
Show InChI InChI=1S/C23H33FN4O2/c1-17(2)21-26-20(19-5-3-4-10-28(19)21)22(29)25-16-23(24)8-11-27(12-9-23)15-18-6-13-30-14-7-18/h3-5,10,17-18H,6-9,11-16H2,1-2H3,(H,25,29)
PDB

UniProtKB/SwissProt

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/an/a 1.36E+3n/an/an/an/a



Suven Life Sciences Ltd.

Curated by ChEMBL


Assay Description
Agonist activity at human 5HT4e receptor expressed in CHO cells assessed as cAMP level after 4 hrs by luciferase reporter gene assay

Eur J Med Chem 103: 289-301 (2015)


Article DOI: 10.1016/j.ejmech.2015.08.051
BindingDB Entry DOI: 10.7270/Q20C4ZST
More data for this
Ligand-Target Pair