BindingDB PrimarySearch

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 6' and Ligand = 'BDBM50334248'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50334248 (1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.40	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Displacement of [3H]LSD from human cloned 5HT6 receptor expressed in human HeLa cells by glass fiber filtration assay				Bioorg Med Chem Lett 21: 346-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.001 BindingDB Entry DOI: 10.7270/Q2P84C5W
Suven Life Sciences Ltd Curated by ChEMBL					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 6 (Homo sapiens (Human))	BDBM50334248 (1-(4-Isopropylbenzenesulfonyl)-3-(4-methylpiperazi...) Show SMILES Show InChI	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	310	n/a	n/a	n/a	n/a	n/a	n/a
Suven Life Sciences Ltd Curated by ChEMBL					Assay Description Antagonist activity at human recombinant 5HT6 receptor expressed in CHO cells assessed as inhibition of 5-HT-stimulated cAMP accumulation by luminome...				Bioorg Med Chem Lett 21: 346-9 (2010) Article DOI: 10.1016/j.bmcl.2010.11.001 BindingDB Entry DOI: 10.7270/Q2P84C5W
Suven Life Sciences Ltd Curated by ChEMBL					More data for this Ligand-Target Pair