Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Merck Sharp & Dohme Research Laboratories Curated by ChEMBL | Assay Description Binding affinity towards human 5-hydroxytryptamine 7 receptor by the displacement of [3H]-5-HT radioligand from the cloned receptor expressed in CHO ... | Bioorg Med Chem Lett 14: 677-80 (2004) BindingDB Entry DOI: 10.7270/Q2CJ8CWS | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Normandie Univ Curated by ChEMBL | Assay Description Antagonist activity at 5-HT7 receptor (unknown origin) | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111705 BindingDB Entry DOI: 10.7270/Q2377D11 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 0.600 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ di Catania Curated by ChEMBL | Assay Description Binding affinity to 5HT7 receptor (unknown origin) assessed as inhibitory constant | Eur J Med Chem 183: (2019) Article DOI: 10.1016/j.ejmech.2019.111690 BindingDB Entry DOI: 10.7270/Q2T72MQ3 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
5-hydroxytryptamine receptor 7 (Homo sapiens (Human)) | BDBM50139355 (2-(6-Phenylpyridin-2-ylthio)-N,N-dimethylethan-ami...) | PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet | Purchase CHEMBL PC cid PC sid UniChem Patents Similars | Article PubMed | 6.20 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Universit£ d'Orl£ans Curated by ChEMBL | Assay Description Displacement of [3H]5CT from human cloned 5HT7B receptor expressed in HEK293 cells | Bioorg Med Chem 18: 1958-67 (2010) Article DOI: 10.1016/j.bmc.2010.01.035 BindingDB Entry DOI: 10.7270/Q2S182M1 | |||||||||||
More data for this Ligand-Target Pair |