Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = '5-hydroxytryptamine receptor 7' and Ligand = 'BDBM50499311'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50499311 (CHEMBL3736156) Show SMILES CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1 |c:18| Show InChI InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	<5.01E+3	n/a	n/a	n/a	n/a	n/a	n/a
Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Antagonist activity at human wild-type 5-HT7 receptor expressed in HEK cells assessed as seretonin-induced cAMP by HTRF assay				J Med Chem 58: 9287-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b01088 BindingDB Entry DOI: 10.7270/Q21C20VP
					More data for this Ligand-Target Pair
5-hydroxytryptamine receptor 7 (Homo sapiens (Human))	BDBM50499311 (CHEMBL3736156) Show SMILES CB1Nc2cccc(OCC(O)CN(C)C)c2C=C1 |c:18| Show InChI InChI=1S/C14H21BN2O2/c1-15-8-7-12-13(16-15)5-4-6-14(12)19-10-11(18)9-17(2)3/h4-8,11,16,18H,9-10H2,1-3H3	PDB Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	n/a	n/a	<5.01E+3	n/a	n/a	n/a	n/a
Janssen Pharmaceutica N.V. Curated by ChEMBL					Assay Description Agonist activity at human wild-type 5-HT7 receptor expressed in HEK cells assessed as cAMP by HTRF assay				J Med Chem 58: 9287-95 (2015) Article DOI: 10.1021/acs.jmedchem.5b01088 BindingDB Entry DOI: 10.7270/Q21C20VP
					More data for this Ligand-Target Pair