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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = '72 kDa type IV collagenase' and Ligand = 'BDBM50298246'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
72 kDa type IV collagenase


(Homo sapiens (Human))
BDBM50298246
PNG
(CHEMBL584358 | N-Hydroxy-5-(3-nitroguanidino)-2-(2...)
Show SMILES NC(NCCC[C@H](NC(=O)Cc1ccccc1)C(=O)NO)=N[N+]([O-])=O |r,w:21.22|
Show InChI InChI=1S/C14H20N6O5/c15-14(18-20(24)25)16-8-4-7-11(13(22)19-23)17-12(21)9-10-5-2-1-3-6-10/h1-3,5-6,11,23H,4,7-9H2,(H,17,21)(H,19,22)(H3,15,16,18)/t11-/m0/s1
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MMDB

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Similars

Article
PubMed
n/an/a 8.70E+3n/an/an/an/an/an/a



Shandong University

Curated by ChEMBL


Assay Description
Inhibition of MMP2


Bioorg Med Chem 17: 4666-73 (2009)


Article DOI: 10.1016/j.bmc.2009.04.056
BindingDB Entry DOI: 10.7270/Q2D21XN3
More data for this
Ligand-Target Pair