BindingDB PrimarySearch

Found 24 hits Enz. Inhib. hit(s) with Target = '85/88 kDa calcium-independent phospholipase A2' and Ligand = 'BDBM50371970'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	46	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPS as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free [14C]-AA formation after 30 mins by sc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in free FA formation after 30 mins by HPLC-MS analysis				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	48	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPG as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	49	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as assessed as reduction in free AA formation after 30 mins...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	54	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant iPLA2 assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS analysis				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	63	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPE as substrate assessed as reduction in 16:0 LPC formation after 30 mins in presenc...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	67	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in free AA formation after 30 mins by HPLC-MS ...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	83	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PLPC as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair
85/88 kDa calcium-independent phospholipase A2 (Homo sapiens (Human))	BDBM50371970 (CHEMBL89506) Show SMILES CCCCCCCCSCC(=O)C(F)(F)F Show InChI	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL DrugBank PC cid PC sid PDB UniChem Similars	Article PubMed	n/a	n/a	160	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of human recombinant calcium-independent PLA2 using PAPA as substrate assessed as reduction in 16:0 LPC formation after 30 mins by HPLC-MS...				J Med Chem 62: 1999-2007 (2019) Article DOI: 10.1021/acs.jmedchem.8b01568 BindingDB Entry DOI: 10.7270/Q27S7S71
University of California Curated by ChEMBL					More data for this Ligand-Target Pair