Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6' and Ligand = 'BDBM429723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429723 (5-(3-(4-(4- chloro-2- methoxyphenyl) piperidin-1- ...) Show SMILES COc1cc(Cl)ccc1C1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C19H24ClN3O4/c1-19(17(25)21-18(26)22-19)8-5-16(24)23-9-6-12(7-10-23)14-4-3-13(20)11-15(14)27-2/h3-4,11-12H,5-10H2,1-2H3,(H2,21,22,25,26)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
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