Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6' and Ligand = 'BDBM429795'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM429795 (5-[3-[4-(4,5- dichloro-2- methoxy- phenyl)-1- pipe...) Show SMILES COc1cc(Cl)c(Cl)cc1C1CCN(CC1)C(=O)CCC1(NC(=O)NC1=O)c1cccc(C)n1 Show InChI InChI=1S/C24H26Cl2N4O4/c1-14-4-3-5-20(27-14)24(22(32)28-23(33)29-24)9-6-21(31)30-10-7-15(8-11-30)16-12-17(25)18(26)13-19(16)34-2/h3-5,12-13,15H,6-11H2,1-2H3,(H2,28,29,32,33)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description The basis for the assay is the cleavage of the substrate 520 MMP FRET substrate XII by human ADAMTS6.The substrate contains sequence Arg-Pro-Lys-Pro-...				US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N
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