Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6' and Ligand = 'BDBM471797'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM471797 (5-[3-[4-(3,4- dichloro-5- methoxy- phenyl) piperaz...) Show SMILES COc1cc(cc(Cl)c1Cl)N1CCN(CC1)C(=O)CCC1(C)NC(=O)NC1=O Show InChI InChI=1S/C18H22Cl2N4O4/c1-18(16(26)21-17(27)22-18)4-3-14(25)24-7-5-23(6-8-24)11-9-12(19)15(20)13(10-11)28-2/h9-10H,3-8H2,1-2H3,(H2,21,22,26,27)	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...				US Patent US10829478 (2020) BindingDB Entry DOI: 10.7270/Q2X351H2
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