Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'A disintegrin and metalloproteinase with thrombospondin motifs 6' and Ligand = 'BDBM471847'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
A disintegrin and metalloproteinase with thrombospondin motifs 6 (Human)	BDBM471847 ((5R)-5-[3-[4-(4- chloro-3-ethoxy- 5-methoxy- pheny...) Show SMILES CCOc1cc(cc(OC)c1Cl)N1CCN(CC1)C(=O)CC[C@@]1(C)NC(=O)NC1=O |r| Show InChI InChI=1S/C20H27ClN4O5/c1-4-30-15-12-13(11-14(29-3)17(15)21)24-7-9-25(10-8-24)16(26)5-6-20(2)18(27)22-19(28)23-20/h11-12H,4-10H2,1-3H3,(H2,22,23,27,28)/t20-/m1/s1	UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	12.5	n/a	n/a	n/a	n/a	n/a	n/a
GALAPAGOS NV US Patent					Assay Description TABLE X: The IC50 value for test compounds can be determined in a fluorescent based protease assay.The basis for the assay is the cleavage of the sub...				US Patent US10829478 (2020) BindingDB Entry DOI: 10.7270/Q2X351H2
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