Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ADAMTS5 (Rattus norvegicus (Rat)) | BDBM429694 (5-methyl-5-(2- methyl-3-oxo- 3-(4-m- tolylpiperidi...) | PDB UniProtKB/TrEMBL GoogleScholar AffyNet | PC cid PC sid UniChem | US Patent | n/a | n/a | 37.5 | n/a | n/a | n/a | n/a | n/a | n/a |
GALAPAGOS NV US Patent | Assay Description The basis for the assay is the cleavage of the substrate TBIS-1 (5 FAM-TEGEARGSVILLK (5TAMRA)K-NH2) (SEQ ID NO: 2) by rnADAMTS-5 (1-564-6H).For the d... | US Patent US10550100 (2020) BindingDB Entry DOI: 10.7270/Q2D2211N | |||||||||||
More data for this Ligand-Target Pair |