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Found 1 hit Enz. Inhib. hit(s) with Target = 'ADP-ribosylhydrolase ARH3' and Ligand = 'BDBM371520'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ADP-ribosylhydrolase ARH3


(Homo sapiens (Human))		BDBM371520
PNG
(N-[1-(Fluoromethyl)cyclopropyl]-1-[(5-methyl-1,2,4...)
Show SMILES Cc1nc(Cn2c3ccc(cc3c(=O)n(Cc3nnc(C)s3)c2=O)S(=O)(=O)NC2(CF)CC2)no1
Show InChI InChI=1S/C20H20FN7O5S2/c1-11-22-16(25-33-11)8-27-15-4-3-13(35(31,32)26-20(10-21)5-6-20)7-14(15)18(29)28(19(27)30)9-17-24-23-12(2)34-17/h3-4,7,26H,5-6,8-10H2,1-2H3
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a>1.50E+5n/an/an/an/an/an/a



Istituto Superiore di Sanita



Assay Description
ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...

J Med Chem 51: 1058-62 (2008)


BindingDB Entry DOI: 10.7270/Q21R6SSM
More data for this
Ligand-Target Pair