Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'ADP-ribosylhydrolase ARH3' and Ligand = 'BDBM421622'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ADP-ribosylhydrolase ARH3 (Homo sapiens (Human))	BDBM421622 (3-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-6-fluo...) Show SMILES FCCn1c2cc(F)c(cc2n(-c2nnc(o2)C(F)F)c1=O)S(=O)(=O)NC1(CF)CC1 Show InChI InChI=1S/C16H14F5N5O4S/c17-3-4-25-9-5-8(19)11(31(28,29)24-16(7-18)1-2-16)6-10(9)26(15(25)27)14-23-22-13(30-14)12(20)21/h5-6,12,24H,1-4,7H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...				US Patent US10995073 (2021) BindingDB Entry DOI: 10.7270/Q28K7D68
					More data for this Ligand-Target Pair
ADP-ribosylhydrolase ARH3 (Homo sapiens (Human))	BDBM421622 (3-[5-(Difluoromethyl)-1,3,4-oxadiazol-2-yl]-6-fluo...) Show SMILES FCCn1c2cc(F)c(cc2n(-c2nnc(o2)C(F)F)c1=O)S(=O)(=O)NC1(CF)CC1 Show InChI InChI=1S/C16H14F5N5O4S/c17-3-4-25-9-5-8(19)11(31(28,29)24-16(7-18)1-2-16)6-10(9)26(15(25)27)14-23-22-13(30-14)12(20)21/h5-6,12,24H,1-4,7H2	PDB UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	>1.50E+5	n/a	n/a	n/a	n/a	n/a	n/a
Cancer Research Technology Limited US Patent					Assay Description ARH3 In vitro selectivity assays were conducted in a total volume of 15 ul in a standard 384 well format. 5 ul of Human Full Length ARH3 (Enzo Life S...				US Patent US10508086 (2019) BindingDB Entry DOI: 10.7270/Q26112QF
					More data for this Ligand-Target Pair