Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM125915'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM125915 (US8765727, 18) Show SMILES Clc1cnc2Nc3cncc(CCc4cc(CNc1n2)ccc4NC(=O)c1ccccc1)c3 Show InChI InChI=1S/C25H21ClN6O/c26-21-15-29-25-30-20-11-17(12-27-14-20)6-8-19-10-16(13-28-23(21)32-25)7-9-22(19)31-24(33)18-4-2-1-3-5-18/h1-5,7,9-12,14-15H,6,8,13H2,(H,31,33)(H2,28,29,30,32)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	>1.00E+3	n/a	n/a	n/a	n/a	7.8	n/a
Incyte Corporation US Patent					Assay Description HTRF kinase assay: 40 μL reactions were run in black 384 well polystyrene plates in assay buffer (50 mM Tris, pH 7.8, 100 mM NaCI, 0.1 mg/mL BSA...				US Patent US8765727 (2014) BindingDB Entry DOI: 10.7270/Q2FQ9V87
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