Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ALK tyrosine kinase receptor' and Ligand = 'BDBM50173124'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ALK tyrosine kinase receptor (Homo sapiens (Human))	BDBM50173124 (CHEMBL3809888) Show SMILES CN1CCN(Cc2ccc(cc2)C(=O)Nc2cc(n[nH]2)-c2ccc(NC(=O)Nc3cccc(F)c3)c(C)c2)CC1 Show InChI InChI=1S/C30H32FN7O2/c1-20-16-23(10-11-26(20)33-30(40)32-25-5-3-4-24(31)17-25)27-18-28(36-35-27)34-29(39)22-8-6-21(7-9-22)19-38-14-12-37(2)13-15-38/h3-11,16-18H,12-15,19H2,1-2H3,(H2,32,33,40)(H2,34,35,36,39)	PDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6.20E+3	n/a	n/a	n/a	n/a	n/a	n/a
National Health Research Institutes Curated by ChEMBL					Assay Description Inhibition of human ALK (1084 to 1410 residues) expressed in baculovirus infected Sf21 insect cells using polyGlu4:Tyr peptide as substrate after 1 h...				J Med Chem 59: 3906-19 (2016) Article DOI: 10.1021/acs.jmedchem.6b00106 BindingDB Entry DOI: 10.7270/Q2Z03B2G
					More data for this Ligand-Target Pair