Compile Data Set for Download or QSAR

Found 5 hits Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM311185'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311185 (US10155760, Example 29 | US10351563, Example 29 | ...) Show SMILES CC(C)CC(C)(COc1ccc(Br)cc1Cl)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C21H25BrClNO3/c1-15(2)12-21(3,14-27-19-10-9-17(22)11-18(19)23)24-20(25)26-13-16-7-5-4-6-8-16/h4-11,15H,12-14H2,1-3H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10155760 (2018) BindingDB Entry DOI: 10.7270/Q2F191S4
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311185 (US10155760, Example 29 | US10351563, Example 29 | ...) Show SMILES CC(C)CC(C)(COc1ccc(Br)cc1Cl)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C21H25BrClNO3/c1-15(2)12-21(3,14-27-19-10-9-17(22)11-18(19)23)24-20(25)26-13-16-7-5-4-6-8-16/h4-11,15H,12-14H2,1-3H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Co. US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10351563 (2019) BindingDB Entry DOI: 10.7270/Q2P55QWS
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311185 (US10155760, Example 29 | US10351563, Example 29 | ...) Show SMILES CC(C)CC(C)(COc1ccc(Br)cc1Cl)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C21H25BrClNO3/c1-15(2)12-21(3,14-27-19-10-9-17(22)11-18(19)23)24-20(25)26-13-16-7-5-4-6-8-16/h4-11,15H,12-14H2,1-3H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10981910 (2021) BindingDB Entry DOI: 10.7270/Q2CF9T6J
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311185 (US10155760, Example 29 | US10351563, Example 29 | ...) Show SMILES CC(C)CC(C)(COc1ccc(Br)cc1Cl)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C21H25BrClNO3/c1-15(2)12-21(3,14-27-19-10-9-17(22)11-18(19)23)24-20(25)26-13-16-7-5-4-6-8-16/h4-11,15H,12-14H2,1-3H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 Cl prepared from 15 μl additions of enzyme and substrates (...				US Patent US10723734 (2020) BindingDB Entry DOI: 10.7270/Q2Z60S4P
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM311185 (US10155760, Example 29 | US10351563, Example 29 | ...) Show SMILES CC(C)CC(C)(COc1ccc(Br)cc1Cl)NC(=O)OCc1ccccc1 Show InChI InChI=1S/C21H25BrClNO3/c1-15(2)12-21(3,14-27-19-10-9-17(22)11-18(19)23)24-20(25)26-13-16-7-5-4-6-8-16/h4-11,15H,12-14H2,1-3H3,(H,24,25)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.670	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX
					More data for this Ligand-Target Pair