Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM427105'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM427105 ((S)-1-(4-(6-fluoroquinolin-4-yl)-2-(trifluoromethy...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(cc1C(F)(F)F)-c1c(F)ccc2ncccc12 |r| Show InChI InChI=1S/C23H24F4N2O/c1-14(2)12-22(3,28)13-30-20-9-6-15(11-17(20)23(25,26)27)21-16-5-4-10-29-19(16)8-7-18(21)24/h4-11,14H,12-13,28H2,1-3H3/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.510	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX
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