Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM427228'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM427228 ((S)-1-((5-(7-chloroquinolin-4-yl)-3-(difluoromethy...) Show SMILES CC(C)C[C@](C)(N)COc1ncc(cc1C(F)F)B1OC(C)(C)C(C)(C)O1 |r| Show InChI InChI=1S/C19H31BF2N2O3/c1-12(2)9-19(7,23)11-25-16-14(15(21)22)8-13(10-24-16)20-26-17(3,4)18(5,6)27-20/h8,10,12,15H,9,11,23H2,1-7H3/t19-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX
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