Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM427308'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM427308 ((S)-1-(4-(2-methoxypyrimidin-4-yl)-2-(trifluoromet...) Show SMILES CC(C)C[C@@](C)(COc1ccc(cc1C(F)(F)F)-c1ccnc(Cl)n1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C23H29ClF3N3O3/c1-14(2)12-22(6,30-20(31)33-21(3,4)5)13-32-18-8-7-15(11-16(18)23(25,26)27)17-9-10-28-19(24)29-17/h7-11,14H,12-13H2,1-6H3,(H,30,31)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	1.40	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM427308 ((S)-1-(4-(2-methoxypyrimidin-4-yl)-2-(trifluoromet...) Show SMILES CC(C)C[C@@](C)(COc1ccc(cc1C(F)(F)F)-c1ccnc(Cl)n1)NC(=O)OC(C)(C)C |r| Show InChI InChI=1S/C23H29ClF3N3O3/c1-14(2)12-22(6,30-20(31)33-21(3,4)5)13-32-18-8-7-15(11-16(18)23(25,26)27)17-9-10-28-19(24)29-17/h7-11,14H,12-13H2,1-6H3,(H,30,31)/t22-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	8.20	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX
					More data for this Ligand-Target Pair