Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM427311'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM427311 ((S)-1-((2-(difluoromethyl)-6-(2-(difluoromethyl)py...) Show SMILES CC(C)C[C@](C)(N)COc1ccc(nc1C(F)F)-c1ccnc(n1)C(F)F |r| Show InChI InChI=1S/C18H22F4N4O/c1-10(2)8-18(3,23)9-27-13-5-4-11(25-14(13)15(19)20)12-6-7-24-17(26-12)16(21)22/h4-7,10,15-16H,8-9,23H2,1-3H3/t18-/m0/s1	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	0.5	n/a	n/a	n/a	n/a	n/a	n/a
Bristol-Myers Squibb Company US Patent					Assay Description The assays were performed in U-bottom 384-well plates. The final assay volume was 30 μl prepared from 15 μl additions of enzyme and substra...				US Patent US10544120 (2020) BindingDB Entry DOI: 10.7270/Q2RF5XCX
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