Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'AP2-associated protein kinase 1' and Ligand = 'BDBM50511377'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50511377 (CHEMBL4534571) Show SMILES Fc1ccc(CS(=O)(=O)Nc2cccc(c2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)cc1 Show InChI InChI=1S/C24H21FN4O3S/c25-19-9-4-15(5-10-19)14-33(31,32)29-20-3-1-2-17(12-20)18-8-11-21-22(13-18)27-28-23(21)26-24(30)16-6-7-16/h1-5,8-13,16,29H,6-7,14H2,(H2,26,27,28,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	59	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill (UNC-CH) Curated by ChEMBL					Assay Description Displacement of Alexafluor labelled kinase tracer236 from biotinylated C-terminal Avi-tagged AAK1 kinase domain (31 to 396 residues) (unknown origin)...				ACS Med Chem Lett 11: 340-345 (2020) Article DOI: 10.1021/acsmedchemlett.9b00399 BindingDB Entry DOI: 10.7270/Q2ZC8669
					More data for this Ligand-Target Pair
AP2-associated protein kinase 1 (Homo sapiens (Human))	BDBM50511377 (CHEMBL4534571) Show SMILES Fc1ccc(CS(=O)(=O)Nc2cccc(c2)-c2ccc3c(NC(=O)C4CC4)n[nH]c3c2)cc1 Show InChI InChI=1S/C24H21FN4O3S/c25-19-9-4-15(5-10-19)14-33(31,32)29-20-3-1-2-17(12-20)18-8-11-21-22(13-18)27-28-23(21)26-24(30)16-6-7-16/h1-5,8-13,16,29H,6-7,14H2,(H2,26,27,28,30)	PDB KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.02E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of North Carolina at Chapel Hill (UNC-CH) Curated by ChEMBL					Assay Description Inhibition of tracer K5 binding to N-terminal nano luciferase-fused AAK1 (unknown origin) expressed in HEK293 cells incubated for 2 hrs followed by N...				ACS Med Chem Lett 11: 340-345 (2020) Article DOI: 10.1021/acsmedchemlett.9b00399 BindingDB Entry DOI: 10.7270/Q2ZC8669
					More data for this Ligand-Target Pair