Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11' and Ligand = 'BDBM50119272'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50119272 ((7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1...) Show SMILES Clc1ccc2N=C(NC3CCC3)NS(=O)(=O)c2c1 |t:5| Show InChI InChI=1S/C11H12ClN3O2S/c12-7-4-5-9-10(6-7)18(16,17)15-11(14-9)13-8-2-1-3-8/h4-6,8H,1-3H2,(H2,13,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	200	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Negative log EC50 for Beta-cell KATP channel				Bioorg Med Chem Lett 12: 2977-80 (2002) BindingDB Entry DOI: 10.7270/Q20V8C4M
					More data for this Ligand-Target Pair
ATP-binding cassette sub-family C member 8/ATP-sensitive inward rectifier potassium channel 11 (Homo sapiens (Human))	BDBM50119272 ((7-Chloro-1,1-dioxo-1,4-dihydro-1lambda*6*-benzo[1...) Show SMILES Clc1ccc2N=C(NC3CCC3)NS(=O)(=O)c2c1 |t:5| Show InChI InChI=1S/C11H12ClN3O2S/c12-7-4-5-9-10(6-7)18(16,17)15-11(14-9)13-8-2-1-3-8/h4-6,8H,1-3H2,(H2,13,14,15)	PDB KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	n/a	n/a	196	n/a	n/a	n/a	n/a
GlaxoSmithKline Research and Development Curated by ChEMBL					Assay Description Inhibition of Beta-cell KATP channel				Bioorg Med Chem Lett 12: 2977-80 (2002) BindingDB Entry DOI: 10.7270/Q20V8C4M
					More data for this Ligand-Target Pair