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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent RNA helicase DDX3X' and Ligand = 'BDBM50540785'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent RNA helicase DDX3X


(Homo sapiens (Human))		BDBM50540785
PNG
(CHEMBL4577525)
Show SMILES CCCCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1ccccc1OC
Show InChI InChI=1S/C19H22N4O3S/c1-3-4-8-15-14-23(22-20-15)16-9-7-10-17(13-16)27(24,25)21-18-11-5-6-12-19(18)26-2/h5-7,9-14,21H,3-4,8H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 180n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...

ACS Med Chem Lett 11: 956-962 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00681
BindingDB Entry DOI: 10.7270/Q2N87FBS
More data for this
Ligand-Target Pair