BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent RNA helicase DDX3X' and Ligand = 'BDBM50540793'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent RNA helicase DDX3X


(Homo sapiens (Human))		BDBM50540793
PNG
(CHEMBL4635553)
Show SMILES COc1cc(NC(=O)Nc2ccccc2C(F)(F)F)ccc1-n1cc(CCC(C)C)nn1
Show InChI InChI=1S/C22H24F3N5O2/c1-14(2)8-9-16-13-30(29-28-16)19-11-10-15(12-20(19)32-3)26-21(31)27-18-7-5-4-6-17(18)22(23,24)25/h4-7,10-14H,8-9H2,1-3H3,(H2,26,27,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 300n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...

ACS Med Chem Lett 11: 956-962 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00681
BindingDB Entry DOI: 10.7270/Q2N87FBS
More data for this
Ligand-Target Pair