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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent RNA helicase DDX3X' and Ligand = 'BDBM50540794'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent RNA helicase DDX3X


(Homo sapiens (Human))		BDBM50540794
PNG
(CHEMBL4633565)
Show SMILES CCCCc1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2NS(C)(=O)=O)cc1
Show InChI InChI=1S/C20H24N6O3S/c1-3-4-7-16-14-26(25-23-16)17-12-10-15(11-13-17)21-20(27)22-18-8-5-6-9-19(18)24-30(2,28)29/h5-6,8-14,24H,3-4,7H2,1-2H3,(H2,21,22,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 60n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...

ACS Med Chem Lett 11: 956-962 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00681
BindingDB Entry DOI: 10.7270/Q2N87FBS
More data for this
Ligand-Target Pair