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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent RNA helicase DDX3X' and Ligand = 'BDBM50540797'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent RNA helicase DDX3X


(Homo sapiens (Human))		BDBM50540797
PNG
(CHEMBL4649465)
Show SMILES CCCC(C)C(F)c1cn(nn1)-c1ccc(NC(=O)Nc2ccccc2C(F)(F)F)cc1
Show InChI InChI=1S/C22H23F4N5O/c1-3-6-14(2)20(23)19-13-31(30-29-19)16-11-9-15(10-12-16)27-21(32)28-18-8-5-4-7-17(18)22(24,25)26/h4-5,7-14,20H,3,6H2,1-2H3,(H2,27,28,32)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.05E+3n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...

ACS Med Chem Lett 11: 956-962 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00681
BindingDB Entry DOI: 10.7270/Q2N87FBS
More data for this
Ligand-Target Pair