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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent RNA helicase DDX3X' and Ligand = 'BDBM50540801'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent RNA helicase DDX3X


(Homo sapiens (Human))		BDBM50540801
PNG
(CHEMBL4633761)
Show SMILES CCOCc1cn(nn1)-c1cccc(c1)S(=O)(=O)Nc1cccc(c1)C(=O)OCC
Show InChI InChI=1S/C20H22N4O5S/c1-3-28-14-17-13-24(23-21-17)18-9-6-10-19(12-18)30(26,27)22-16-8-5-7-15(11-16)20(25)29-4-2/h5-13,22H,3-4,14H2,1-2H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5n/an/an/an/an/an/a



Universit£ degli Studi di Siena

Curated by ChEMBL


Assay Description
Inhibition of recombinant full length human His-tagged DDX3X expressed in Escherichia coli using dsRNA as substrate measured after 40 mins in presenc...

ACS Med Chem Lett 11: 956-962 (2020)


Article DOI: 10.1021/acsmedchemlett.9b00681
BindingDB Entry DOI: 10.7270/Q2N87FBS
More data for this
Ligand-Target Pair