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Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-dependent translocase ABCB1' and Ligand = 'BDBM50249856'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
ATP-dependent translocase ABCB1


(Homo sapiens (Human))		BDBM50249856
PNG
(12-(Dimethylamino)-2,3,6,7-tetrahydro-9-(N-piperid...)
Show SMILES [#6]\[#7+](-[#6])=[#6]-1\[#6]=[#6]-[#6]-2=[#6](-c3ccc(s3)-[#6](=S)-[#7]-3-[#6]-[#6]-[#6]-[#6]-[#6]-3)-c3cc4-[#6]-[#6]-[#6]-[#7]-5-[#6]-[#6]-[#6]-c(c3[Te][#6]-2=[#6]-1)c4-5 |c:4,6,38|
Show InChI InChI=1S/C31H34N3S2Te/c1-32(2)21-10-11-22-27(19-21)37-30-23-9-7-17-33-16-6-8-20(29(23)33)18-24(30)28(22)25-12-13-26(36-25)31(35)34-14-4-3-5-15-34/h10-13,18-19H,3-9,14-17H2,1-2H3/q+1
PDB

UniProtKB/SwissProt

B.MOAD
antibodypedia
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars
Article
PubMed
n/an/a 1.40E+4n/an/an/an/an/an/a



The State University of New York

Curated by ChEMBL


Assay Description
Inhibition of human MDR1 expressed in MDCK2 cells assessed as enhancement of Calcein-AM uptake treated 30 mins before Calcein-AM challenge measured a...

J Med Chem 52: 3328-41 (2009)


Article DOI: 10.1021/jm900253g
BindingDB Entry DOI: 10.7270/Q29Z94SF
More data for this
Ligand-Target Pair