Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM161035'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM161035 (US9108947, 6) Show SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CN1CCCCC1CNC(CO)c1ccc2C(=O)OCc2c1C |r| Show InChI InChI=1S/C28H34N2O6/c1-16-19(6-8-21-23(16)14-35-27(21)33)25(13-31)29-11-18-5-3-4-10-30(18)12-26(32)20-7-9-22-24(17(20)2)15-36-28(22)34/h6-9,18,25-26,29,31-32H,3-5,10-15H2,1-2H3/t18?,25?,26-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	446	n/a	n/a	n/a	n/a	7.4	37
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...				US Patent US9108947 (2015) BindingDB Entry DOI: 10.7270/Q2V40SZT
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