Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM161045'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM161045 (US9108947, 20) Show SMILES Cc1c2COC(=O)c2ccc1[C@@H](O)CNC1CCCN(C1)c1ccc(cn1)[N+]#[C-] |r| Show InChI InChI=1S/C22H24N4O3/c1-14-17(6-7-18-19(14)13-29-22(18)28)20(27)11-24-16-4-3-9-26(12-16)21-8-5-15(23-2)10-25-21/h5-8,10,16,20,24,27H,3-4,9,11-13H2,1H3/t16?,20-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	52	n/a	n/a	n/a	n/a	7.4	37
Merck Sharp & Dohme Corp. US Patent					Assay Description Block of Kir1.1 (ROMK1) currents was examined by whole cell voltage clamp (Hamill et. al. Pfluegers Archives 391:85-100 (1981)) using the IonWorks.RT...				US Patent US9108947 (2015) BindingDB Entry DOI: 10.7270/Q2V40SZT
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