Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'ATP-sensitive inward rectifier potassium channel 1' and Ligand = 'BDBM196032'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
ATP-sensitive inward rectifier potassium channel 1 (Homo sapiens (Human))	BDBM196032 (US9206199, 137) Show SMILES Fc1ccc([C@H]2CN3CCN(C[C@H]3CO2)C(=O)Cc2cnc(nc2)-n2cnnn2)c(Cl)c1[N+]#[C-] |r| Show InChI InChI=1S/C21H19ClFN9O2/c1-24-20-16(23)3-2-15(19(20)22)17-10-30-4-5-31(9-14(30)11-34-17)18(33)6-13-7-25-21(26-8-13)32-12-27-28-29-32/h2-3,7-8,12,14,17H,4-6,9-11H2/t14-,17+/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Merck Sharp & Dohme Corp. US Patent					Assay Description The ROMK channel functional thallium flux assay is performed in 384 wells, using the FLIPR-Tetra instrument. HEK-hKir1.1 cells are seeded in Poly-D-L...				US Patent US9206199 (2015) BindingDB Entry DOI: 10.7270/Q2VH5MND
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