Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
Acid ceramidase (Homo sapiens (Human)) | BDBM50392472 (CHEMBL408217) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Fondazione Istituto Italiano di Tecnologia Curated by ChEMBL | Assay Description Inhibition of acid ceramidase (unknown origin) | J Med Chem 56: 3518-30 (2013) Article DOI: 10.1021/jm301879g BindingDB Entry DOI: 10.7270/Q27D2WH5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Homo sapiens (Human)) | BDBM50392472 (CHEMBL408217) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
TBA | Assay Description Inhibition of acid ceramidase in human HaCaT cell lysates | Citation and Details Article DOI: 10.1021/acs.jmedchem.0c01561 BindingDB Entry DOI: 10.7270/Q2G73JC2 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Homo sapiens (Human)) | BDBM50392472 (CHEMBL408217) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 1.00E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Humboldt Universit£t zu Berlin Curated by ChEMBL | Assay Description Inhibition of aCDase | Bioorg Med Chem 20: 6162-70 (2012) Article DOI: 10.1016/j.bmc.2012.08.031 BindingDB Entry DOI: 10.7270/Q29Z960Z | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
Acid ceramidase (Homo sapiens (Human)) | BDBM50392472 (CHEMBL408217) | PDB UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet | Purchase CHEMBL MCE PC cid PC sid UniChem | Article PubMed | n/a | n/a | 2.77E+4 | n/a | n/a | n/a | n/a | n/a | n/a |
Medical University of South Carolina Curated by ChEMBL | Assay Description Inhibition of ACDase in human MCF7 cell lysate using [9,10-3H] De-C16-Cer substrate after 1 hr by scintillation counting analysis | Bioorg Med Chem 22: 6933-44 (2014) Article DOI: 10.1016/j.bmc.2014.10.025 BindingDB Entry DOI: 10.7270/Q24M964R | |||||||||||
More data for this Ligand-Target Pair |