Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Acid-sensing ion channel 1' and Ligand = 'BDBM50510037'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid-sensing ion channel 1 (Mus musculus)	BDBM50510037 (CHEMBL4463769) Show SMILES Cc1nn(c(C)c1-c1cccc(F)c1)-c1ncnc2CNCc12 Show InChI InChI=1S/C17H16FN5/c1-10-16(12-4-3-5-13(18)6-12)11(2)23(22-10)17-14-7-19-8-15(14)20-9-21-17/h3-6,9,19H,7-8H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Promidis Curated by ChEMBL					Assay Description Inhibition of pH 6.6-stimulated mouse ASIC1a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay				ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 BindingDB Entry DOI: 10.7270/Q2RB77Z0
					More data for this Ligand-Target Pair