Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acid-sensing ion channel 2' and Ligand = 'BDBM50510041'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acid-sensing ion channel 2 (Mus musculus)	BDBM50510041 (CHEMBL4476781) Show SMILES Cc1nn(c(C)c1-c1ccc(CN)cc1)-c1ccc(CN)cc1 Show InChI InChI=1S/C19H22N4/c1-13-19(17-7-3-15(11-20)4-8-17)14(2)23(22-13)18-9-5-16(12-21)6-10-18/h3-10H,11-12,20-21H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Promidis Curated by ChEMBL					Assay Description Inhibition of pH 6.25-stimulated mouse ASIC1a/2a heterodimer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence...				ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 BindingDB Entry DOI: 10.7270/Q2RB77Z0
					More data for this Ligand-Target Pair
Acid-sensing ion channel 2 (Mus musculus)	BDBM50510041 (CHEMBL4476781) Show SMILES Cc1nn(c(C)c1-c1ccc(CN)cc1)-c1ccc(CN)cc1 Show InChI InChI=1S/C19H22N4/c1-13-19(17-7-3-15(11-20)4-8-17)14(2)23(22-13)18-9-5-16(12-21)6-10-18/h3-10H,11-12,20-21H2,1-2H3	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem	Article PubMed	n/a	n/a	>3.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Promidis Curated by ChEMBL					Assay Description Inhibition of pH 5.5-stimulated mouse ASIC2a homomer expressed in CHOK1 cells assessed as reduction in channel activation by VSD fluorescence assay				ACS Med Chem Lett 10: 627-632 (2019) Article DOI: 10.1021/acsmedchemlett.8b00591 BindingDB Entry DOI: 10.7270/Q2RB77Z0
					More data for this Ligand-Target Pair