Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Acrosin' and Ligand = 'BDBM50382109'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acrosin (Homo sapiens (Human))	BDBM50382109 (CHEMBL2023319) Show SMILES Clc1ccc(-c2cc(C=O)no2)c(Cl)c1 Show InChI InChI=1S/C10H5Cl2NO2/c11-6-1-2-8(9(12)3-6)10-4-7(5-14)13-15-10/h1-5H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of human acrosin using N-alpha-benzoyl-L-arginine p-nitroanilide as substrate after 3 hrs by spectrophotometry				Bioorg Med Chem Lett 24: 2802-6 (2014) Article DOI: 10.1016/j.bmcl.2014.04.118 BindingDB Entry DOI: 10.7270/Q2J38V4S
					More data for this Ligand-Target Pair
Acrosin (Homo sapiens (Human))	BDBM50382109 (CHEMBL2023319) Show SMILES Clc1ccc(-c2cc(C=O)no2)c(Cl)c1 Show InChI InChI=1S/C10H5Cl2NO2/c11-6-1-2-8(9(12)3-6)10-4-7(5-14)13-15-10/h1-5H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+5	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of human sperm acrosin using BAPNA as substrate after 3 hrs by spectrophotometric analysis				Bioorg Med Chem Lett 23: 4177-84 (2013) Article DOI: 10.1016/j.bmcl.2013.05.031 BindingDB Entry DOI: 10.7270/Q25Q4XHT
					More data for this Ligand-Target Pair
Acrosin (Homo sapiens (Human))	BDBM50382109 (CHEMBL2023319) Show SMILES Clc1ccc(-c2cc(C=O)no2)c(Cl)c1 Show InChI InChI=1S/C10H5Cl2NO2/c11-6-1-2-8(9(12)3-6)10-4-7(5-14)13-15-10/h1-5H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	1.70E+6	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of acrosin in human spermatozoa assessed as effect on amidase activity after 3 hrs incubation by spectrophotometry				Bioorg Med Chem Lett 22: 3554-9 (2012) Article DOI: 10.1016/j.bmcl.2012.03.042 BindingDB Entry DOI: 10.7270/Q2HT2QBG
					More data for this Ligand-Target Pair
Acrosin (Homo sapiens (Human))	BDBM50382109 (CHEMBL2023319) Show SMILES Clc1ccc(-c2cc(C=O)no2)c(Cl)c1 Show InChI InChI=1S/C10H5Cl2NO2/c11-6-1-2-8(9(12)3-6)10-4-7(5-14)13-15-10/h1-5H	PDB Reactome pathway KEGG UniProtKB/SwissProt antibodypedia GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.90E+7	n/a	n/a	n/a	n/a	n/a	n/a
Second Military Medical University Curated by ChEMBL					Assay Description Inhibition of human acrosin using N-alpha-benzoyl-DL-arginine para-nitroanilide-HCl as substrate after 3 hrs by spectrophotometry				Eur J Med Chem 59: 176-82 (2013) Article DOI: 10.1016/j.ejmech.2012.11.005 BindingDB Entry DOI: 10.7270/Q23X87ZB
					More data for this Ligand-Target Pair