Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Activated CDC42 kinase 1' and Ligand = 'BDBM419723'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM419723 (US10464919, Example 61) Show SMILES Clc1cc(ccc1C#N)N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C24H24ClN5O/c25-21-13-18(5-4-17(21)14-26)30-10-8-29(9-11-30)15-16-3-6-19-22(12-16)28-24(31)20-2-1-7-27-23(19)20/h3-6,12-13,27H,1-2,7-11,15H2,(H,28,31)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.80	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
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