Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Activated CDC42 kinase 1' and Ligand = 'BDBM419759'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM419759 (US10464919, Example 97) Show SMILES O=C(NC1CC1)c1ccc(nc1)N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1 Show InChI InChI=1S/C26H30N6O2/c33-25(29-19-5-6-19)18-4-8-23(28-15-18)32-12-10-31(11-13-32)16-17-3-7-20-22(14-17)30-26(34)21-2-1-9-27-24(20)21/h3-4,7-8,14-15,19,27H,1-2,5-6,9-13,16H2,(H,29,33)(H,30,34)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem	US Patent	n/a	n/a	3.70	n/a	n/a	n/a	n/a	n/a	n/a
Je Il Pharmaceutical Co., Ltd. US Patent					Assay Description The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...				US Patent US10464919 (2019) BindingDB Entry DOI: 10.7270/Q2736T8M
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