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Found 1 hit Enz. Inhib. hit(s) with Target = 'Activated CDC42 kinase 1' and Ligand = 'BDBM419793'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Activated CDC42 kinase 1


(Homo sapiens (Human))
BDBM419793
PNG
(US10464919, Example 131)
Show SMILES COc1ccc(nn1)N1CCN(Cc2ccc3c4NCCCc4c(=O)[nH]c3c2)CC1
Show InChI InChI=1S/C22H26N6O2/c1-30-20-7-6-19(25-26-20)28-11-9-27(10-12-28)14-15-4-5-16-18(13-15)24-22(29)17-3-2-8-23-21(16)17/h4-7,13,23H,2-3,8-12,14H2,1H3,(H,24,29)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
antibodypedia
GoogleScholar
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PC cid
PC sid
UniChem
US Patent
n/an/a 2.81n/an/an/an/an/an/a



Je Il Pharmaceutical Co., Ltd.

US Patent


Assay Description
The tankyrase-1 or tankyrase-2 enzyme inhibitory activities of the compounds of the present invention were assayed in the following manner by use of ...


US Patent US10464919 (2019)


BindingDB Entry DOI: 10.7270/Q2736T8M
More data for this
Ligand-Target Pair