Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Activated CDC42 kinase 1' and Ligand = 'BDBM98370'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM98370 (US8481733, 182) Show SMILES Nc1nccn2c(nc(-c3ccc(Oc4cccc(F)c4)cc3)c12)C1CCC1 Show InChI InChI=1S/C22H19FN4O/c23-16-5-2-6-18(13-16)28-17-9-7-14(8-10-17)19-20-21(24)25-11-12-27(20)22(26-19)15-3-1-4-15/h2,5-13,15H,1,3-4H2,(H2,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	109	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, LLC US Patent					Assay Description AlphaScreen (amplified luminescent proximity homogeneous assay) assay was used to test for ACK1 inhibitory activity.				US Patent US8481733 (2013) BindingDB Entry DOI: 10.7270/Q2XD109J
					More data for this Ligand-Target Pair
Activated CDC42 kinase 1 (Homo sapiens (Human))	BDBM98370 (US8481733, 182) Show SMILES Nc1nccn2c(nc(-c3ccc(Oc4cccc(F)c4)cc3)c12)C1CCC1 Show InChI InChI=1S/C22H19FN4O/c23-16-5-2-6-18(13-16)28-17-9-7-14(8-10-17)19-20-21(24)25-11-12-27(20)22(26-19)15-3-1-4-15/h2,5-13,15H,1,3-4H2,(H2,24,25)	PDB MMDB KEGG UniProtKB/SwissProt B.MOAD DrugBank antibodypedia GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
OSI Pharmaceuticals, LLC Curated by ChEMBL					Assay Description Inhibition of ACK1 (unknown origin) by biochemical assay				Bioorg Med Chem Lett 23: 979-84 (2013) Article DOI: 10.1016/j.bmcl.2012.12.042 BindingDB Entry DOI: 10.7270/Q2348MQT
					More data for this Ligand-Target Pair