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Compile Data Set for Download or QSAR

Found 1 hit Enz. Inhib. hit(s) with Target = 'Activin receptor type-1' and Ligand = 'BDBM50466192'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Activin receptor type-1


(Homo sapiens (Human))		BDBM50466192
PNG
(CHEMBL4280585)
Show SMILES NS(=O)(=O)c1ccc(-c2cnn3cc(cnc23)-c2ccc(nc2)N2CCNCC2)c2ccccc12
Show InChI InChI=1S/C25H23N7O2S/c26-35(33,34)23-7-6-20(19-3-1-2-4-21(19)23)22-15-30-32-16-18(14-29-25(22)32)17-5-8-24(28-13-17)31-11-9-27-10-12-31/h1-8,13-16,27H,9-12H2,(H2,26,33,34)
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KEGG

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PC cid
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Article
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n/an/a 422n/an/an/an/an/an/a



National Center for Advancing Translational Sciences

Curated by ChEMBL


Assay Description
Inhibition of ALK2 (unknown origin) using Ulight topo IIa (Thr 1342) peptide as substrate preincubated for 10 mins followed by substrate addition and...

Bioorg Med Chem Lett 28: 3356-3362 (2018)


Article DOI: 10.1016/j.bmcl.2018.09.006
BindingDB Entry DOI: 10.7270/Q2NZ8BBT
More data for this
Ligand-Target Pair