Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50005979'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50005979 (CHEMBL46510 | Octadec-9-enoic acid (2,6-dimethyl-p...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)Nc1c(C)cccc1C Show InChI InChI=1S/C26H43NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-25(28)27-26-23(2)20-19-21-24(26)3/h11-12,19-21H,4-10,13-18,22H2,1-3H3,(H,27,28)/b12-11-	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Tested in vitro to inhibit Acyl coenzyme A:cholesterol acyltransferase in intestinal microsomes isolated from cholesterol-fed rabbits.				J Med Chem 35: 1609-17 (1992) BindingDB Entry DOI: 10.7270/Q2G44QXN
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50005979 (CHEMBL46510 | Octadec-9-enoic acid (2,6-dimethyl-p...) Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)Nc1c(C)cccc1C Show InChI InChI=1S/C26H43NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-22-25(28)27-26-23(2)20-19-21-24(26)3/h11-12,19-21H,4-10,13-18,22H2,1-3H3,(H,27,28)/b12-11-	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	43	n/a	n/a	n/a	n/a	n/a	n/a
Warner-Lambert Company Curated by ChEMBL					Assay Description Acyl coenzyme A:cholesterol acyltransferase (ACAT), inhibition by incubation with [1-14C]oleolyl-CoA and intestinal microsomes isolated from intestin...				J Med Chem 36: 1662-8 (1993) BindingDB Entry DOI: 10.7270/Q21Z4522
					More data for this Ligand-Target Pair