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Found 1 hit Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50005993'   
Target/Host
(Institution)		LigandTarget/Host
Links		Ligand
Links		Trg + Lig
Links		Ki
nM		ΔG°
kJ/mole		IC50
nM		Kd
nM		EC50/IC50
nM		koff
s-1		kon
M-1s-1		pHTemp
°C
Acyl-CoA:cholesterol acyltransferase


(Oryctolagus cuniculus)		BDBM50005993
PNG
(2,2-Dimethyl-tetradecanoic acid (2,4,6-trimethoxy-...)
Show SMILES CCCCCCCCCCCCC(C)(C)C(=O)Nc1c(OC)cc(OC)cc1OC
Show InChI InChI=1S/C25H43NO4/c1-7-8-9-10-11-12-13-14-15-16-17-25(2,3)24(27)26-23-21(29-5)18-20(28-4)19-22(23)30-6/h18-19H,7-17H2,1-6H3,(H,26,27)
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PubMed
n/an/a 63n/an/an/an/an/an/a



Warner-Lambert Company

Curated by ChEMBL


Assay Description
In vitro inhibition of acyl coenzyme A:cholesterol acyltransferase, in intestinal microsomes isolated from cholesterol-fed rabbits

J Med Chem 35: 1609-17 (1992)


BindingDB Entry DOI: 10.7270/Q2G44QXN
More data for this
Ligand-Target Pair