Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50047502'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047502 (1-{2-Dimethylamino-6-[3-(4-naphthalen-1-yl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2cccc3ccccc23)cccc1N(C)C Show InChI InChI=1S/C30H37N5O2/c1-4-5-8-18-31-30(36)33-29-27(34(2)3)16-10-17-28(29)37-20-11-19-35-21-26(32-22-35)25-15-9-13-23-12-6-7-14-24(23)25/h6-7,9-10,12-17,21-22H,4-5,8,11,18-20H2,1-3H3,(H2,31,33,36)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	65	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047502 (1-{2-Dimethylamino-6-[3-(4-naphthalen-1-yl-imidazo...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2cccc3ccccc23)cccc1N(C)C Show InChI InChI=1S/C30H37N5O2/c1-4-5-8-18-31-30(36)33-29-27(34(2)3)16-10-17-28(29)37-20-11-19-35-21-26(32-22-35)25-15-9-13-23-12-6-7-14-24(23)25/h6-7,9-10,12-17,21-22H,4-5,8,11,18-20H2,1-3H3,(H2,31,33,36)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.55E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair