Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50047509'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047509 (1-{2-Dimethylamino-6-[3-(5-phenyl-tetrazol-2-yl)-p...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2nnc(n2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C24H33N7O2/c1-4-5-9-16-25-24(32)26-22-20(30(2)3)14-10-15-21(22)33-18-11-17-31-28-23(27-29-31)19-12-7-6-8-13-19/h6-8,10,12-15H,4-5,9,11,16-18H2,1-3H3,(H2,25,26,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	23	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047509 (1-{2-Dimethylamino-6-[3-(5-phenyl-tetrazol-2-yl)-p...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2nnc(n2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C24H33N7O2/c1-4-5-9-16-25-24(32)26-22-20(30(2)3)14-10-15-21(22)33-18-11-17-31-28-23(27-29-31)19-12-7-6-8-13-19/h6-8,10,12-15H,4-5,9,11,16-18H2,1-3H3,(H2,25,26,32)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents	PubMed	n/a	n/a	230	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair