Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50047510'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047510 (1-{2-Dimethylamino-6-[2-(4-phenyl-imidazol-1-yl)-e...) Show SMILES CCCCCNC(=O)Nc1c(OCCn2cnc(c2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C25H33N5O2/c1-4-5-9-15-26-25(31)28-24-22(29(2)3)13-10-14-23(24)32-17-16-30-18-21(27-19-30)20-11-7-6-8-12-20/h6-8,10-14,18-19H,4-5,9,15-17H2,1-3H3,(H2,26,28,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	170	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047510 (1-{2-Dimethylamino-6-[2-(4-phenyl-imidazol-1-yl)-e...) Show SMILES CCCCCNC(=O)Nc1c(OCCn2cnc(c2)-c2ccccc2)cccc1N(C)C Show InChI InChI=1S/C25H33N5O2/c1-4-5-9-15-26-25(31)28-24-22(29(2)3)13-10-14-23(24)32-17-16-30-18-21(27-19-30)20-11-7-6-8-12-20/h6-8,10-14,18-19H,4-5,9,15-17H2,1-3H3,(H2,26,28,31)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	PubMed	n/a	n/a	1.40E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit aorta homogenate.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair