Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Acyl-CoA:cholesterol acyltransferase' and Ligand = 'BDBM50047526'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047526 (1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-imid...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(OC)cc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O3/c1-5-6-7-16-28-27(33)30-26-24(31(2)3)10-8-11-25(26)35-18-9-17-32-19-23(29-20-32)21-12-14-22(34-4)15-13-21/h8,10-15,19-20H,5-7,9,16-18H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair
Acyl-CoA:cholesterol acyltransferase (Oryctolagus cuniculus)	BDBM50047526 (1-(2-Dimethylamino-6-{3-[4-(4-methoxy-phenyl)-imid...) Show SMILES CCCCCNC(=O)Nc1c(OCCCn2cnc(c2)-c2ccc(OC)cc2)cccc1N(C)C Show InChI InChI=1S/C27H37N5O3/c1-5-6-7-16-28-27(33)30-26-24(31(2)3)10-8-11-25(26)35-18-9-17-32-19-23(29-20-32)21-12-14-22(34-4)15-13-21/h8,10-15,19-20H,5-7,9,16-18H2,1-4H3,(H2,28,30,33)	PDB Reactome pathway KEGG UniProtKB/TrEMBL DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	PubMed	n/a	n/a	1.33E+3	n/a	n/a	n/a	n/a	n/a	n/a
Eisai Company, Ltd. Curated by ChEMBL					Assay Description Tested for inhibition against acyl coenzyme A:cholesterol acyltransferase from rabbit intestine microsomes.				J Med Chem 36: 1630-40 (1993) BindingDB Entry DOI: 10.7270/Q22B8X4P
					More data for this Ligand-Target Pair